Serotonin Syndrom

Arzneiverordnung in der Praxis, Ausgabe 3/1998 (Seite 7 ff). Seit der Einführung neuerer Antidepressiva vom Typ der selektiven Serotonin- Wiederaufnahme-Hemmer (Selective Serotonin Reuptake Inhibitors; SSRIs), die zur Behandlung vielfältiger psychiatrischer Erkankungen, wie Depressionen, Zwangsstörungen, Bulimie oder... (20 seitiges ...

Serotonin syndrome is a condition characterized by dangerously high levels of serotonin - a chemical produced by nerve cells - in your body...

An adverse drug reaction to serotonergic agents, ie 5-HT (5-hydroxytryptamine) agonists. It can occur as a consequence of normal therapeutic drug use, self-poisoning or drug interactions. The syndrome is not caused by an idiopathic reaction, rather it is a foreseeable consequence of excessive stimulation of CNS and peripheral serotonin receptors. ...

Das Serotonin-Syndrom manifestiert sich üblicherweise nach der Dosiserhöhung einer serotoninergen Substanz oder durch die Kombination mehrerer serotoninerger Stoffe. Es sind jedoch auch einzelne Fälle in Zusammenhang mit einer Monotherapie bekannt... (3 seitiger PDF-Artikel)

Serotonin syndrome was first described in medical literature in 1959 in a patient with tuberculosis who was treated with meperidine. But it wasn’t given its current name until 1982. Recognizing the early signs is tricky because it has varying symptoms that can be easily confused with less serious conditions, including tremor, diarrhea, high blood ...